The 2025 Stand Up to Cancer fundraiser will be hosted by Sheryl Crow and feature Dolly Parton, and is set to be broadcast from Nashville for the first time on August 15. This one-hour special will take place at The Pinnacle, a new 4,500 capacity venue in Music City, and will bring together musicians, celebrities, athletes, cancer survivors, and medical professionals, to raise money and awareness for cancer research. Additional performers and appearances will  be announced in the coming weeks. The commercial-free broadcast will be shown on over 30 platforms, including all major TV networks and streaming services.

“The goal of Stand Up To Cancer has always been about working collaboratively to push cancer research forward so we could help patients as quickly as possible,” SU2C co-founder Katie Couric said in a statement. “Nearly two decades later, it’s incredibly gratifying and inspiring to see the impact of this research. Bringing the show to Nashville will infuse new energy and excitement into our mission.” (Billboard)